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13C-NMR spectroscopy plays an important role in the elucidation of organic compound structures. Chemists researching new compounds will find this volume, which covers the 13C-NMR data of diterpenes, a valuable reference source.

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The First International Symposium and Pakistan-U.S. Binational Workshop on Natural Product Chemistry represents the first international conference ever to be organised in Pakistan on chemistry. For many years I had aspired to organise such a con­ ference, and finally when it materialised in February 1984, it brought together the very best in the field. The result was as expected - a most stimulating series of lectures and discussions, all of w...

Nuclear magnetic resonance spectroscopy is presently going through an explosive phase of development. This has been brought about largely on account of the advent of Fourier transform NMR spectrometers linked to powerful microcomputers which have opened up a whole new world for structural chemists and biochemists. This is exemplified by a host of publications, especially on new pulse sequences, which continue to provide new exciting modificati...

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products ra...

Nuclear magnetic resonance spectroscopy is presently going through an explosive phase of development. This has been brought about largely on account of the advent of Fourier transform NMR spectrometers linked to powerful microcomputers which have opened up a whole new world for structural chemists and biochemists. This is exemplified by a host of publications, especially on new pulse sequences, which continue to provide new exciting modificati...

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The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery an...

The world's population is multiplying day-by-day and development projects need to be built to accomplish the desires of new generations. Almost all development projects have unwanted environmental consequences. In this book the conceptual framework is more empirical and provides an in-depth analysis of environmental impacts. The analysed data is presented in the form maps, diagrams and tables to communicate the results. The book highlights wid...

Advances in natural product chemistry have led to a large number of drugs, both derived from medicinal plants, marine plants, and animals, and created as synthetic analogues of these sources. This ground-breaking, comprehensive volume presents the latest data on the 13C-NMR of monoterpenes and sesquiterpenes.

The present volume contains contributions from a number of leading natural product chemists. The syntheses of the avermectin-milbemycin family of antiparasitic agents, macrolide antibiotics, beta-lactam antibiotics, beta-methylcarbapenem derivatives, taxane diterpenes and tumour-promoting diterpenes, indolizidines and indol(2, 3-a)carbazole alkaloids, 2-amino alcohols are described. Moreover, one contribution deals with the generation of catio...

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