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Regulation of Membrane Na+-K+ ATPase

Dhalla, Naranjan S / Chakraborti, Sajal
Regulation of Membrane Na+-K+ ATPase
Na+-K+ ATPase or Na-pump ATPase, a member of “P”-type ATPase superfamily, is characterized by association of multiple isoforms mainly of it’s α- and β- subunits. At present four different α- (α-1, α-2, α-3 and α-4) and three β- (β-1, β-2, and β-3) isoforms have been identified in mammalian cells and their differential expressions are tissue specific. Regulation of Na+-K+ ATPase activity is an important but a complex process, which involves sho...

CHF 188.00

Proteases in Health and Disease

Dhalla, Naranjan S. / Chakraborti, Sajal
Proteases in Health and Disease
Proteases form one of the largest and most diverse families of enzymes known. Once considered primarily as “enzymes of digestion, ” it is now clear that proteases are involved in every aspect of cellular function. Members of the diverse families of proteases act to promote cellular proteolysis found in nature, and their deregulation may result in different pathophysiological conditions, such as tumor progression, vascular remodeling, atheroscl...

CHF 188.00

Proteases in Physiology and Pathology

Dhalla, Naranjan S. / Chakraborti, Sajal
Proteases in Physiology and Pathology
Using a multidisciplinary approach, this book describes the biochemical mechanisms associated with dysregulation of proteases and the resulting pathophysiological consequences. It highlights the role and regulation of different types of proteases as well as their synthetic and endogenous inhibitors. The role of proteases was initially thought to be limited to general metabolic digestion. However, we now know that the role of protein breakdown ...

CHF 188.00

Proteases in Health and Disease

Dhalla, Naranjan S. / Chakraborti, Sajal
Proteases in Health and Disease
Proteases form one of the largest and most diverse families of enzymes known. Once considered primarily as “enzymes of digestion, ” it is now clear that proteases are involved in every aspect of cellular function. Members of the diverse families of proteases act to promote cellular proteolysis found in nature, and their deregulation may result in different pathophysiological conditions, such as tumor progression, vascular remodeling, atheroscl...

CHF 188.00

Role of Proteases in Cellular Dysfunction

Dhalla, Naranjan S. / Chakraborti, Sajal
Role of Proteases in Cellular Dysfunction
It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play a role in a variety of biological functions ranging from digestion, fertilization, development to senescence and death. Under physiological conditions the ability of proteases is regulated by endogenous inhibitors. However, when the activity of proteases is not regulated appropriately, disease processes ca...

CHF 205.00