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Designing a Platform Technology for Pediatric Drug Delivery

Dhananjay M, More
Designing a Platform Technology for Pediatric Drug Delivery
The aim of present work was to utilize low temperature hot melt extrusion (HME) as a novel technology to mask bitter taste of Tenofovir DF (TDF), Furosemide (FUR) and Clarithromycin (CLR) and to develop a flexible and palatable solid oral dosage form to improve patient compliance. Pediatric patients need different oral dosage forms than adults due to differences in swallowing capabilities, taste likings, and dosage requirement. A manipulation ...

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