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Bioactive compounds have a range of chemical structures and biological activities. Recently, new advances regarding natural compounds were achieved, leading to their application in several areas related to human therapies. New computational methods that analyze the pharmacological potential of natural products have led to its its conversion into low toxicity molecules. This Special Issue has collected the most recent innovations in scientific ...

This volume discusses gardens as designed landscapes of mediation between nature and culture, embodying different levels of human control over wilderness, defining specific rules for this confrontation and staging different forms of human dominance.

In the last two decades insulin signalling and protection in brain has emerged as a novel field of research.Although growing evidence supports the hypothesis that dysfunction of neuronal glucose utilization and metabolism and/or in insulin receptor signal transduction cascade is involved in Alzheimer's disease pathogenesis, the role of insulin on oxidative stress- and diabetes-induced neuronal dysfunction and death has been less investigated.T...

Many people have sought to define neurolinguistic programming-otherwise known as NLP. John Grinder said, "NLP is the epistemology of returning to what we have lost a state of grace." Richard Bandler said, "NLP is an attitude which is an insatiable curiosity about human beings with a methodology that leaves behind it a trail of techniques." And Robert Dilts said, "NLP is whatever works." No matter how you define it, NLP has the potential to tra...

As birras das crianças são uma característica do desenvolvimento normal das crianças e surgem por volta dos 15-18 meses que, normalmente, são desencadeadas devido ao desejo de independência e à incapacidade de escolher por parte das crianças. Para que as birras não se tornem um grave problema de comportamento das crianças, os pais devem adoptar práticas educativas adequadas para promover comportamentos desejáveis. O presente estudo analisou se...

Factores relacionados a la farmacología de los AINE, ciertas características del huésped y factores relacionados con los hábitos de consumo se asocian y podrían explicar las reacciones adversas a los antiinflamatorios no esteroideos, considerado actualmente un problema de salud pública. Por lo tanto, al determinar posibles mecanismos patogénicos y los factores asociados se podría desarrollar medidas de prevención oportunas.