14 Ergebnisse.

In the past few years nucleic acids technologies have grown into a powerful analytical and also increasingly therapeutic tool. It has been applied not only to the uncovering of gene functions in many organisms, but also to pathogenetic analysis and recently also for the treatment of human diseases. The book discusses in depth the potential of these innovative methods in the broad field of central nervous system and brain tumours particularly. ...

Developments over the past few years have revealed the remarkable versatility of RNA in any compartment of the cell, tasks that had been thought to be exclusively in the realm of proteins and even beyond. The chapters in this book written by leading investigators in the field provide insight into various promising avenues where RNA and nucleic acid derivatives including antisense RNAs, such as siRNA, miRNAs, amplification/selection (SELEX) gen...

Cardiovascular disease is the number one cause of death worldwide. In 2005 17.5 million people, representing 30% of all global deaths, died of cardiovascular disease. For this reason every effort needs to be made to improve the early diagnosis and treatment procedures for combating this disease. This book - edited by Professors Erdmann and Barciszewski, both internationally recognised experts in the field of RNA molecular biology, and Professo...

Small non coding RNAs (ncRNAs), also known as the secret regulators of the cells, have been discovered only 20 years ago, and it has been much more recently that the attention of the scientific community has been turned towards the structure and function of ncRNAs in plants. Indeed, it has been found that the higher the organisms have been developed, the larger the numbers of ncRNA genes encoded in their DNAs. With this book the editors have b...

The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-...

This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology, the establishment of the genetic code, isomerization of RNA, damage of nucleobases in RNA, the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport, molecular crowding by the use of ionic liquids, new technologies enabling the modifica...

For this RNA Technologies volume a world-wide outstanding group of RNA specialists are contributing the most recent developments in this fast moving field of RNA molecular biology. The book features up-to-date information of our current knowledge on antisense, ribozyme, micro RNA, and DNAzyme strategies, as well as on other small RNAs from eukaryotes and prokaryotes, and the employment of chemical modifications to stabilize ribonucleic acids f...

Small non coding RNAs (ncRNAs), also known as the secret regulators of the cells, have been discovered only 20 years ago, and it has been much more recently that the attention of the scientific community has been turned towards the structure and function of ncRNAs in plants. Indeed, it has been found that the higher the organisms have been developed, the larger the numbers of ncRNA genes encoded in their DNAs. With this book the editors have b...

In the past few years nucleic acids technologies have grown into a powerful analytical and also increasingly therapeutic tool. It has been applied not only to the uncovering of gene functions in many organisms, but also to pathogenetic analysis and recently also for the treatment of human diseases. The book discusses in depth the potential of these innovative methods in the broad field of central nervous system and brain tumours particularly. ...

The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-...

Developments over the past few years have revealed the remarkable versatility of RNA in any compartment of the cell, tasks that had been thought to be exclusively in the realm of proteins and even beyond. The chapters in this book written by leading investigators in the field provide insight into various promising avenues where RNA and nucleic acid derivatives including antisense RNAs, such as siRNA, miRNAs, amplification/selection (SELEX) gen...

DNA and RNA nanobiotechnologies have currently reached the status of one of the most dynamic research areas in the field of drug delivery in molecular medicine. Scientists and bio-engineers are creating totally new nanometer-scale structures with unique biological properties for a wide range of medical applications. The book, written by world-leading scientists in this new field, gives an overview of various aspects and applications of DNA and...

This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology, the establishment of the genetic code, isomerization of RNA, damage of nucleobases in RNA, the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport, molecular crowding by the use of ionic liquids, new technologies enabling the modifica...

Cardiovascular disease is the number one cause of death worldwide. In 2005 17.5 million people, representing 30% of all global deaths, died of cardiovascular disease. For this reason every effort needs to be made to improve the early diagnosis and treatment procedures for combating this disease. This book - edited by Professors Erdmann and Barciszewski, both internationally recognised experts in the field of RNA molecular biology, and Professo...