Statins
Grua, Benedetta La / Molinelli, Alessandro
Statins work by reducing cholesterol synthesis by inhibiting the enzyme HMG-CoA reductase. The decrease in cholesterol levels is associated with increased expression of receptors of hepatocytes, with a greater extraction of plasma LDL-C and a lower diffusion of it into the tissues. In this book, the authors present current research in the study of the pharmacology, clinical implications and adverse effects of statins. Topics include the pleiot...