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Chemotherapy by Gold(III) complex

Hassan, Firas / Abdul-Hameed, A. / Yousif, Emad
Chemotherapy by Gold(III) complex
High-throughput and high-content analysis of cultured cells or even small organisms are of imminent importance in drug discovery, toxicology and in individualized medicine. In medicine, the identification of tailored patient-specific therapy is important in cancer, chronic inflammation, infection and other diseases. High Content Screening was developed with the perspective of the history of the development of the automated DNA sequencers that ...

CHF 71.00

Computational Immunology

Hassan, Khaled / Badr, Amr / Nabil, Emad
Computational Immunology
Vaccination is a method of stimulating resistant in the human body to specific diseases using microorganisms (bacteria or viruses) that have been modified or killed. Currently, the available vaccines are composed of killed or life attenuated the whole pathogens before being injected to the human body. Despite the advantages of such vaccines, there are a lot of potential safety problems such as incomplete inactivation of the killed pathogens or...

CHF 71.00

In-vitro Cytochrome P450s effect in breast cancer

Hassan, Firas / Abd-Allateef, Mays / Yousif, Emad
In-vitro Cytochrome P450s effect in breast cancer
Hormone therapy is the first targeted therapy also called estrogen suppression therapy often used as an adjuvant therapy to reduce the risk of cancer back after surgery or cancer that has spread. Aromatase inhibitors such as (anastrozole) are a common type of the hormone therapy, it interferes with the body's ability to produce estrogen from androgen by suppressing aromatase enzyme in post-menopausal women with positive estrogen receptor breas...

CHF 47.50

In-vitro Cytochrome P450s effect in breast cancer

Hassan, Firas / Abd-Allateef, Mays / Yousif, Emad
In-vitro Cytochrome P450s effect in breast cancer
Aromatase inhibitors use two distinct mechanisms to block the action of aromatase and thereby reduce estrogen production. Type I inhibitors such as exemestane and formestane (Lentaron) are androgen-like compounds that bind irreversibly to the substrate-complex, causing permanent inactivation of the enzyme. This could potentially lead to prolonged estrogen deprivation even after the drug is cleared. These drugs are also known as aromatase inact...

CHF 71.00