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This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, repr...

Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspect...

The various cell types have traditionally been recognized and classified according to their appearance in the light microscope following the process of fixing, processing, sectioning, and staining tissues that is known as histology. Classical histology has been augmented byimmunohistochemistry (the use of specific antibodies to stain particular molecular species "in situ"). Immunohistochemistry has allowed the identification of many more cell ...

This fourteenth volume of the series provides comprehensive, current information on the diagnosis, therapy and prognosis of brain tumors and spinal tumors. For the readers' convenience, contributions are organized into three categories of Pineal Tumors, Pituitary Tumors, and Spinal Tumors. Readers will find discussion of various aspects of a number of tumor types, including angiocentric glioma, pilomyxoid astrocytoma, pituicytoma, pediatric lo...

This is the thirteenth volume in a series which presents current understanding of stem cells and cancer stem cells. This book presents many relevant topics including the different sources of cancer stem cells: the features, roles and clinical potential of stem cells emerge from engaging with this comprehensive work. Chapters explore molecular mechanisms underlying human somatic cell reprogramming to generate induced pluripotent stem cells, and...

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection and Aging, Volume 4 - Mitophagy presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson's Disease, cardiac aging, and skeletal muscle atrophy. The most c...

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This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer, and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of d...

In this second volume in the series exploring Tumor Dormancy, Quiescence, and Cellular Senescence, discussion is focused on the role of tumor dormancy in diseases such as breast cancer, melanoma, prostate cancer, liver cancer and lung cancer. M. A. Hayat, the series editor, writes in the preface that little is known of factors regulating the transition of residual cancer into a dormant state or the subsequent reinitiation of growth. A majority...

Each year, tens of millions of people are respectively. The following data indicate diagnosed worldwide with cancer, and the burden (seriousness) of gastrointestinal more than half of these patients eventu- cancer, liver cancer, and colorectal cancers ally die from this disease. The severity of globally and in the United States. (Table 1) the burden of cancer becomes really clear Surgical and molecular therapies and pr- by knowing that there w...

This is the first book that discusses the subjects of diagnosis, therapy, therapy assessment, and prognosis of lung and prostate cancer in one single volume. Cancer killed 6.7 million people around the world in 2002, and this figure is expected to rise to 10.1 million in 2020. Lung cancer has been the most common cancer in the world since 1985, and by 2002 there were 1.35 million new cases, representing 12.5% of all new cancers. It was also th...

This sixth volume in the series Methods of Cancer Diagnosis, Therapy, and Prognosis discusses Ovarian Cancer, Renal Cancer, Urogenitary Cancer, Urinary Bladder Cancer, Cervical Uterine Cancer, Skin Cancer, Leukemia, Multiple Myeloma and Sarcoma. Both standard and emerging therapies for these cancers, written by expert oncologists/pathologists in this field, are included. This fully illustrated volume Identifies biomarkers based on genetic alt...

The author's primary aim is to thoroughly explain the biochemical concepts governing cytochemical procedures for transmission electron microscopy. Such information provides undergraduate and graduate students, technicians, and researchers with a more profound understanding of electron micrographs, as well as the knowledge to refine existing techniques and develop new methodologies.

This two-volume reference book will present imaging technology currently used in clinics or at experimental stages for diagnosis and/or early detection of various cancers, including anticancer vaccines, surgical techniques, chemotherapy, radiation, and gene therapies. Cancers discussed will include breast, lung, liver, prostate, cervical, brain, gastrointestinal, ovarian, gallbladder, esophageal, head and neck, bronchial, bone, thyroid, pancre...

This volume presents a detailed survey of imaging, multidetector-row computed t- various methodologies related to diagno- ography, helical computed tomography, sis, therapy, and prognosis of liver cancer, ultrasonography, and power Doppler ult- including colorectal liver metastases and sound, for the prognosis and assessment of biliary tract carcinomas, while the already liver cancer treatment (including HCC) and published Volumes 1, 2, 3, and...

This fourth volume in the series Methods of Cancer Diagnosis, Therapy and Prognosis discusses various methodologies for the diagnosis, therapy and prognosis of Colorectal Cancer. Both standard and emerging therapies for this cancer, written by expert oncologists/pathologists in this field, are included.   This fully illustrated volume: * Presents surgical, radiological, and molecular therapies and prognostic markers for colorectal cancer. * Hi...

With cancer related deaths projected to rise to 10.3 million people by 2020, the need to prevent, diagnose, and cure cancer is greater than ever. These two volumes present readers with the most up-to-date imaging instrumentation, general and diagnostic applications for various cancers. Both volumes discuss the various imaging techniques used to locate and diagnose tumors, including ultrasound, X-ray, color Doppler sonography, PET, CT, PET/CT, ...

This is the first book that discusses subjects of diagnosis, therapy, therapy assessment, and prognosis of breast cancer in one single volume.   Cancer killed 6.7 million people around the world in 2002 and this figure is expected to rise to 10.1 million in 2020. Approximately, 189, 510 new cases of breast cancer were reported in 2007 in the United States, and 40, 910 died in the same year. Focusing on Breast Carcinoma, this first volume in th...

This eighth volume in the series Methods of Cancer Diagnosis, Therapy, and Prognosis discusses in detail the classification of the CNS tumors as well as brain tumor imaging. Scientists and Clinicians have contributed state of the art chapters on their respective areas of expertise, providing the reader a whole field view of the CNS tumors and brain tumor imaging in Europe. This fully illustrated volume: Explains the genetics of malignant brai...