Apoptosis and Cancer Chemotherapy
Hickman, John a / Dive, Caroline
The past few years have witnessed an astonishing international effort that established the role of some 20 new molecules in apoptosis and added activation or suppression of apoptosis to the accepted biological functions of a great many others already familiar in cancer biology. Some of these molecules are receptors, transducing cytokine-mediated signals, others appear to intensify or diminish the risk that a compro mised cell will fire its ap...