Maturation Phenomenon in Cerebral Ischemia
Ito, U. / Klatzo, I. / Kuroiwa, T. / Kirino, T.
It has been well recognized that following an ischemic
insult many nerve cells of the brain are not killed
outright, but may suffer a "delayed neuronal death" or even
recover. This led to the concept of "maturation phenomenon"
with its main implication that the maturation of ischemic
lesions may provide a "window of opportunity" i.e. a period
of time when the injury to neuronal elements is still
reversible, and during which an applicati...