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This volume provides reviews of six topics demonstrating the breadth of the field and recent successes in medicinal chemistry. Each of the first five chapters takes an important biochemical target as its theme and provides an insight into current progress in drug design. The last chapter focuses on the vital subject of phamacokinetics and the great strides that have been made in this discipline during the past decade. All chapers provide an in...

The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a ???quality lead???, where these ???quality leads??? come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifi...

Annual Review of Eclectic Developments in Medicinal Chemistry *Presents the latest research in the field of drug discovery *Publishes on a twice yearly basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect