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Examines the cases of several historic and high-profile drugs in order to discuss the future of the pharmaceutical industry.

A thorough examination of the chemistry and history of ten prominent prescription drugs.

Chinese Fingernail Image Diagnosis (FID) allows an individual's health to be assessed by an image formed from blood and Qi or Chi (energy) between the nail bed and nail plate. This concise guide to FID covers its origins, the application of FID in common disorders and methods of examination, and features illustrations and detailed case examples.

The up-to-DATE guide to name reactions in heterocyclic chemistry Name Reactions in Heterocyclic Chemistry II presents a comprehensive treatise on name reactions in heterocyclic chemistry, one of the most exciting-and important-fields within organic chemistry today. The book not only covers fresh ground, but also provides extensive information on new and/or expanded reactions in: * Three- and four-membered heterocycles * Five-membered heteroc...

Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all ...

C¿H activation involves any of a wide range of techniques, often using catalysts in which a carbon to hydrogen covalent bond of an organic compound is cleaved to replace the hydrogen with a functional group. C¿H Activation for functionalization is the state of the art in organic chemistry. It enables chemists to carry out reactions in the most environmentally friendly fashion with the least contamination of by-products. Written by an author ex...

In this fifth edition of Jack Jie Li's seminal "Name Reactions", the author has added twenty-seven new name reactions to reflect the recent advances in organic chemistry. As in previous editions, each reaction is delineated by its detailed step-by-step, electron-pushing mechanism and supplemented with the original and the latest references, especially from review articles. Now with addition of many synthetic applications, this book is not only...

In this fifth edition of Jack Jie Li's seminal "Name Reactions", the author has added twenty-seven new name reactions to reflect the recent advances in organic chemistry. As in previous editions, each reaction is delineated by its detailed step-by-step, electron-pushing mechanism and supplemented with the original and the latest references, especially from review articles. Now with addition of many synthetic applications, this book is not only...

Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in the field review more than 100 years of findings, explaining their relevance to contempor...

This book covers all aspects of the medicinal chemistry of the latest drugs, and the cutting-edge science associated with them. Following on the editors' well-received prior books, this illustrates how chemistry, biology, pharmacokinetics, and a host of disciplines come together to produce successful medicines.

Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies develop...

Palladium chemistry, despite its immaturity, has rapidly become an indispensable tool for synthetic organic chemists. Heterocycles are of paramount importance in the pharmaceutical industry and palladium chemistry is one of the most novel and efficient ways of making heterocycles. Today, palladium-catalyzed coupling is the method of choice for the synthesis of a wide range of biaryls and heterobiaryls. The number of applications of palladium c...

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Covers important name reactions relevant to heterocyclic chemistry The field of heterocyclic chemistry has long presented a special challenge for chemists. Because of the enormous amount and variety of information, it is often a difficult topic to cover for undergraduate and graduate chemistry students, even in simplified form. Yet the chemistry of heterocyclic compounds and methods for their synthesis form the bedrock of modern medicinal chem...

This set collects all the volumes in the well-established and authoritative series on name reactions in organic chemistry. These are key reactions that have found widespread application in all areas of organic synthesis: medicinal / pharmaceutical, agricultural, fine chemicals, and polymer science.

This guide provides a comprehensive and authoritative review of name reactions on homologation. Each section includes a description of the reaction, the historical perspective, a mechanism for the reaction, variations and improvements on the reaction, synthetic utilities of the reaction, experimental details, and current references to the primary literature. The primary topics include organometallics (palladium, organozinc, organocopper, other...

The all-inclusive book on the cutting-edge science driving the medicinal chemistry of the latest drugs The successor to the editors' two highly acclaimed works on drug synthesis, Contemporary Drug Synthesis and The Art of Drug Synthesis, this book provides refocused and extensive new coverage detailing how chemistry, biology, and pharmacokinetics integrate to spearhead successful medical findings. Modern Drug Synthesis carries on the mission ...

This book continues in this well-established series of works by presenting a comprehensive treatise on name reactions in homologation reactions. Each section includes a description of the reaction, the historical perspective, a mechanism for the reaction, variations and improvements on the reaction, synthetic utilities of the reaction, experimental details, and references to the current primary literature. Primary topics include organometallic...

A valuable additon to the literature by any measure and surely will prove its merit in years to come. The new knowledge that arises with its help will be impressive and of great benefit to humankind." --From the Foreword by E.J. Corey, Nobel laureate An invaluable guide to name reactions on carbocyclic ring formations Ring-forming reactions have found widespread applicability advantageous to the interests of science. Currently, they are used...