Gene expression during carcinogenesis: A bioinformatics p...
Manyam, Ganiraju / Baranova, Ancha![Gene expression during carcinogenesis: A bioinformatics perspective](https://support.digitalhusky.com/media/annotations/sorted/713/7133039/CHSBZCOP037133039.jpg)
Cancer arises from a stepwise accumulation of genetic changes through expansion of the malignant cell clones in the population of pre-malignant cells undergoing Darwinian selection process. In other words, cancer is an outcome of continuous and random acquisition of the changes in the genomes of individual cells. These modifications gradually and progressively change the phenotype of the normal cell making it more malignant through a loss of a...