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Digitale Daten gelten sowohl als Quelle für Wirtschaftswachstum, Innovation und Arbeitsplätze wie auch als Treiber der datenbasierten Reorganisation praktisch aller gesellschaftlichen Bereiche ("Datafizierung"). Die datenökonomisch befeuerten Transformationsprozesse des Sozialen werfen dementsprechend vielfältige Fragen auf: Welche Daten sollen von wem wie verwertbar sein? Wie lässt sich legitime Verfügungsmacht gestalten? Usw. Der Band behand...

Cementitious materials are being widely used as solidification/stabilisation and barrier materials for a variety of chemical and radioactive wastes, primarily due to their favourable retention properties for metals, radionuclides and other contaminants. The retention properties result from various mineral phases in hydrated cement that possess a high density and diversity of reactive sites for the fixation of contaminants through a variety of ...

With the advent of high-throughput technologies, the number of genes of interest has expanded and the traditional methods for gene function analysis cannot achieve the throughput necessary for large-scale exploration. In Gene Function Analysis, a select team of experts bring together a number of recently developed techniques for studying gene function.  The volume begins with a variety of computational techniques, which provide an excellent po...

With the advent of high-throughput technologies following completion of the human genome project and similar projects, the number of genes of interest has expanded and the traditional methods for gene function analysis cannot achieve the throughput necessary for large-scale exploration. This book brings together a number of recently developed techniques for looking at gene function, including computational, biochemical and biological methods a...

Die Kunst des Cover-DesignsSchallplattencover sind mehr als nur profane Schutzhüllen, sie sind immer auch Spiegel und Ausdruck ihrer Zeit. Wie die Musik auf einer Schallplatte, sprechen auch sie unsere Gefühle an - Liebe, Leben, Tod, Mode oder Rebellion. Viele Menschen verbinden mit einem bestimmten Cover auch eine ganz spezielle Situation oder Stimmung in ihrem Leben. Einige sind mindestens so legendär geworden wie die Musik, für die sie steh...

The determination of protein function has been a major goal of molecular biology since the founding of the discipline. However, as we learn more about gene function, we discover that the context within which a gene is expressed controls the specific function of that gene. It has become critical to establish the background in which gene function is determined and to perform experiments in multiple applicable backgrounds.  In Gene Function Analy...

This volume is a welcome extension of the on-going dialogue in the world of music librarianship that might reach a wider audience than the electronic discussion list of the Music Libraries Association or the more abstruse columns of Music References Services Quarterly, Notea, or Fontes Artis Musica. For this reason it deserves wide promotion and readership, espousing as it does so passionately some very fundamental values in Western culture."-...

In the past two decades, the large investment in cancer research led to identification of the complementary roles of genetic mutation and epigenetic change as the fundamental drivers of cancer. With these discoveries, we now recognize the deep heterogeneity in cancer, in which phenotypically similar behaviors in tumors arise from different molecular aberrations. Although most tumors contain many mutations, only a few mutated genes drive carcin...

Cementitious materials are being widely used as solidification/stabilisation and barrier materials for a variety of chemical and radioactive wastes, primarily due to their favourable retention properties for metals, radionuclides and other contaminants. The retention properties result from various mineral phases in hydrated cement that possess a high density and diversity of reactive sites for the fixation of contaminants through a variety of ...

The determination of protein function has been a major goal of molecular biology since the founding of the discipline. However, as we learn more about gene function, we discover that the context within which a gene is expressed controls the specific function of that gene. It has become critical to establish the background in which gene function is determined and to perform experiments in multiple applicable backgrounds.  In Gene Function Analy...

In the past two decades, the large investment in cancer research led to identification of the complementary roles of genetic mutation and epigenetic change as the fundamental drivers of cancer. With these discoveries, we now recognize the deep heterogeneity in cancer, in which phenotypically similar behaviors in tumors arise from different molecular aberrations. Although most tumors contain many mutations, only a few mutated genes drive carcin...

In Berlin-Buch, an der Peripherie der heutigen Großstadt gelegen, trafen um 1900 zwei Welten aufeinander. Das idyllische Dorf mit einer sehenswerten Barockkirche, einem Gutshof und einem Schlosspark wurde mit seiner Feldflur vom Berliner Magistrat gekauft und zu einem großstädtischen Gesundheitsstandort ausgebaut. Die zur Zeit des Ersten Weltkriegs größtenteils fertig gestellte Krankenhausstadt Buch mit zwei "Irrenanstalten", zwei Lungensanato...