Antisense Technology: Methods of Delivery and RNA Studies
Rose, Macy
Antisense RNA (asRNA) refers to a type of single-stranded RNA. It hybridizes with protein coding messenger RNA (mRNA) and complements it to inhibit its translation into a protein. Eukaryotes and prokaryotes, both have naturally occuring asRNAs in them. They can be divided into two types including short and long non-coding RNAs (ncRNAs). asRNAs primarily control the gene expression and are widely utilized as tools for gene knockdown. Antisense ...