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Filling a gap in the literature of biophysical methodology, this book explains the fundamentals in the theory and practice of AUC. It introduces the basic principles and technical setup of an AUC experiment and describes the optical systems used for detection. It explores the ultracentrifugation experiment from a macromolecular standpoint, offer

Analytical ultracentrifugation consists of the application of a high gravitational field to a solution of particles and the real-time detection of the evolving spatial concentration gradients. When applied to macromolecules or nanoscopic particles, ultracentrifugation data can provide rich information on macromolecular shape, solvation, composition and size-distribution. This is the first comprehensive overview book on AUC to be published sinc...