Cellular Reprogramming in Stirred Suspension Bioreactors
Shafa, Mehdi
The clinical application of stem cells depends on the availability of large number of pluripotent cells that are not restricted by ethical, immunological and technical considerations. Induced Pluripotent Stem cells (iPSCs) have been recently achieved by reprogramming of mouse and human somatic cells by expression of defined transcription factors. Reprogramming of differentiated cells through this technology is a valuable tool to find out the m...