Signal Transduction and the Coordination of B Lymphocyte ...
Siminovitch, Katherine A. / Justement, Louis B.![Signal Transduction and the Coordination of B Lymphocyte Development and Function I](https://support.digitalhusky.com/media/annotations/sorted/154/15420599/CHSBZCOP0315420599.jpg)
Proper development and differentiation of B lymphocytes is es sential to ensure that an organism has the ability to mount an effective humoral immune response against foreign antigens. The immune system must maintain a balance between the deletion of harmful self-reactive B cells and the generation of a diverse rep ertoire of B cells that has the ability to recognize an almost un limited array of foreign antigens. The need to delete self-re...