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Characterizing Bacterial Secretion Systems Using Mass Spe...

Singh, Pragya / R. Goodlett, David
Characterizing Bacterial Secretion Systems Using Mass Spectrometry
Gram-negative bacteria have evolved an array of secretion systems for protein transport across their membranes. The ability to secrete a diverse set of proteins to their target of choice provides bacteria with a menacing tool for pathogenesis. This work aims to enhance our understanding of bacterial pathogenesis by characterizing key aspects of bacterial secretion systems using mass spectrometry. Chapter 1 provides a general introduction of pr...

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