Pharmacokinetics and Metabolism in Drug Design
Smith, Dennis A. / Allerton, Charlotte / Kalgutkar, Amit S. / Waterbeemd, Han van de / Walker, Don K. / Mannhold, Raimund / Kubinyi, Hugo / Folkers, Gerd
In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have been made, with new topics such as pro-drugs, active metabolites and transporters covered in detail in a manner useful to the Drug Discovery scientist. The authors discuss the p...