mTOR activates PKB/Akt and PKC-¿ in Cardiac Hypertrophy
Villiger, Ludwig
Many people are suffering from cardiac hypertrophy, which can lead to heart failure. The numbers of patients, who are dying because of heart failure, are increasing. Therefore it is important to understand the underlying molecular mechanism of this disease. In cardiac hypertrophy the heart tries to catch up with the increased afterload by increasing the proteinbiosynthesis and cell growth making its ventricular walls thicker. In the beginning,...