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This book delineates how systems biology, pharmacogenomic, and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model. The text reviews and discusses approaches that can be used as effective tools to dissect mechanisms underlying pharmacological and toxicological phenomena associated with the exposure to drugs or environmental toxicants during development.

How preclinical research approaches can inform clinical interventions-and vice versa Because of the complexity and temporal features of the developing brain, the developing nervous system may be more susceptible to neurotoxic insults. The study of neurodevelopmental toxicology has great potential for helping to advance the understanding of brain-related biological processes, including neuronal plasticity, neurodegeneration/regeneration, toxic...