In 1804, while a student at Oxford, Thomas De Quincey was looking for relief from excruciating pain when a college acquaintance recommended opium. "Opium!" De Quincey wrote. "Dread agent of unimaginable pleasure and pain! I had heard of it as I had of manna or of ambrosia, but no further: how unmeaning a sound it was at that time!" Confessions of an English Opium-Eater, De Quincey's best-known work, is an account of his early life and opium ad...
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