21 Ergebnisse - Zeige 1 von 20.

Our understanding of the mechanisms and management of cardiac arrhythmias has improved dramatically in recent years thanks to continuing basic research coupled with technological advances. 'Fast Facts: Cardiac Arrhythmias' translates this improved understanding into straightforward guidance for managing patients presenting with signs of cardiac arrhythmia. The third edition of this highly readable handbook has been thoroughly updated to includ...

Pyruvate kinase deficiency is a rare genetic disease that causes red blood cells to break apart. Despite an ever-growing understanding of the disease, it remains unfamiliar to many healthcare professionals, and the information available to patients is limited. This superbly illustrated workbook is designed to help patients equip themselves with the best information about their condition to improve the conversations they have about it with thei...

This last year has seen the approval of the first targeted treatments for acute myeloid leukemia (AML) - following decades with no new developments and a poor prognosis for most patients with the disease. The new drugs reflect the remarkable progress that has been made in our understanding of the pathophysiology of AML and its underlying cytogenetic and molecular abnormalities - which differ not only between patients but also within a patient ...

You may be unfamiliar with pyruvate kinase (PK) deficiency. It is a rare inherited enzyme disorder that affects the glycolytic pathway used by red blood cells to generate energy, manifesting as hemolytic anemia. The symptoms vary greatly between individuals, making diagnosis difficult, and management primarily comprises supportive treatments. Written by experts in the field, 'Fast Facts: Pyruvate Kinase Deficiency' provides a comprehensive int...

Biosimilars have been in clinical use for more than 10 years, and evidence from more than 700 million patient-days' exposure shows that approved biosimilars can be used as safely and effectively as their originator biologics. And yet concerns about these drugs persist, particularly in therapy areas where they are recent additions to the formulary. It is vital to address these concerns so that clinicians can prescribe biosimilars with confidenc...

An in-depth look at a rare disease Myasthenia gravis (MG) is a rare autoimmune disorder of the neuromuscular junction, characterized by muscle fatigability. Patients often initially present with ocular symptoms, but in most cases the disease spreads beyond the eye muscles to more generalized involvement of bulbar, facial, neck, proximal limb and respiratory muscles. With adequate treatment, most patients with MG are able to live productive liv...

Our understanding of the biology of bladder cancer has advanced remarkably since the second edition of 'Fast Facts: Bladder Cancer' was published in 2006. Five new immunotherapies targeting the PD-1 axis were approved in 2016 and 2017 for the treatment of advanced bladder cancer, reflecting this transformative explosion in knowledge about the biology of the disease. This new era of targeted treatment offers hope to patients, particularly those...

The treatment of cancer is being revolutionized by drugs that modulate the immune system, offering the prospect of long-term response and extended survival for many patients with advanced incurable cancer. A plethora of new drugs are being incorporated into current standards of care but many questions remain unanswered - and new ones emerge - about how to use these exciting new drugs to best effect. A good understanding of immune-oncology is t...

Our understanding of multiple myeloma (MM) is growing at a formidable pace, particularly in terms of risk factors and potential drug targets. Minimal residual disease (MRD) negativity is set to become the new benchmark in treatment, and cytogenetic analysis is now paving the way for personalized therapies. This second edition of 'Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias' includes: - the new IMWG SLiM CRAB criteria - the latest a...

Worldwide, osteoarthritis is one of the most rapidly rising conditions associated with disability. For most people, it is a syndrome of joint pain and stiffness, with associated functional problems that have a substantial effect on quality of life. As well as expert advice on well-established diagnostic criteria and the latest practical treatment information, this comprehensive handbook provides: . updates on the genetics of the disease . nove...

All health professionals, regardless of specialty, will care for patients with pain that has persisted for more than 6 months. This fully updated fourth edition of 'Fast Facts: Chronic and Cancer Pain', written by two internationally renowned experts in the field, is designed to bring busy health professionals up to speed with the latest information in this area, including: . Easy-to-read overviews of pain mechanisms . A practical approach to ...

Effective new treatments - from drugs to surgery to devices - are revolutionizing both outcome and wellbeing in patients with heart failure. Written with the non-specialist in mind, this practical resource distills a lot of complex information into a refreshingly readable format, with clear informative diagrams and useful pull-out tables. Highlights include: . a concise discussion of the pathophysiological mechanisms that lead to heart failure...

Since the last edition of this book, 'no evidence of disease activity' (NEDA) has been proposed as a new treatment target, early data on the first pharmacological treatments for progressive MS have emerged, and the first remyelination trial has shown positive effects on nerve repair. It is with this sense of optimism that the authors of 'Fast Facts: Multiple Sclerosis' have detailed the latest developments for use in clinical practice by all m...

When it comes to detecting, diagnosing and treating women who have, or are suspected of having, ovarian cancer, there are significant opportunities for well-informed healthcare professionals to intervene in a meaningful way. 'Fast Facts: Ovarian Cancer' examines the areas that will have the biggest effect in clinical practice, including: . the evidence for and against screening . the valuable role of genetic testing in identifying at-risk wome...

Prostate cancer is unusual among solid tumors in that the majority of affected men die with, rather than of, the disease. This presents many challenges to healthcare professionals and patients in terms of deciding if, when and how to intervene in order to control tumor growth and spread, thereby extending survival but without compromising quality of life. This is the ninth edition of 'Fast Facts: Prostate Cancer' since 1996, testament to the r...

Hypertension is the biggest cause of death and disability in the world, yet it remains underdiagnosed, undertreated and, in many cases, poorly controlled. As in the previous edition, 'Fast Facts: Hypertension' advises on: . accurate measurement of blood pressure and problems such as 'white-coat' hypertension . routine assessments for people with high blood pressure . other modifiable risk factors (smoking, high cholesterol levels etc.) . non-p...

Keine Beschreibung.

Cutaneous T-cell lymphoma (CTCL) is one of the 'great mimickers'. To be certain of the diagnosis, there must be clear correlation between the pathological and clinical findings, making collaboration between clinicians and pathologists essential. Knowing the patient's history, lesion description and diagnostic work-up will help the pathologist make a more informed decision with respect to the histopathology under the microscope. Likewise, under...

Rapid developments in the classification, screening and treatment of non-small-cell lung cancer (NSCLC) are improving outcomes for patients with the disease. This insightful guide is designed to bring you up to speed with recent advances, including: . the latest CT-based screening and interval growth imaging techniques . proposed changes to the TNM classification system . the increasing trend for minimally invasive and lung-sparing surgery . s...

Ulcerative colitis and Crohn's disease, referred to collectively as inflammatory bowel disease (IBD), are chronic debilitating disorders. IBD, particularly Crohn's disease, is increasing everywhere, most notably in the Western world where about 1 in 200 people now has the condition. This highly readable, 'zippy' fifth edition of 'Fast Facts: Inflammatory Bowel Disease' provides succinct yet thorough information that will aid early recognition ...