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Cancer drug discovery has been and continues to be a process of ingenuity, serendip­ ity, and dogged determination. In an effort to develop and discover better therapies against cancer, investigators all over the world have increased our knowledge of cell biology, biochemistry, and molecular biology. The goal has been to define therapeuti­ cally exploitable differences between normal and malignant cells. The result has been an increased unders...

Three eminent scientists, each well known for the clarity of their writing, present for students and researchers what is known about the internal structure, origin and evolution of White Dwarfs, Neutron Stars and Black Holes, all objects at the final stage of stellar evolution. They cover fascinating topics such as pulsation of white dwarfs, millisecond pulsars or the dynamics around black holes. The book is written for graduate students in as...

Ausgehend von der Frage, mit welchen Sanktionen Insidergeschäfte an der Börse belegt werden sollten, hat die Verfasserin eine grundlegende Untersuchung zur Insiderproblematik vorgenommen, die im Ergebnis zu einem differenzierten Vorschlag für die Strafvorschrift im neuen Wertpapierhandelsgesetz (WpHG) führt. Nach einer Einführung in die Problematik wird die Frage erörtert, warum Insidergeschäfte überhaupt verboten werden sollen. Die Verfasser...

Model Based Fuzzy Control uses a given conventional or fuzzy open loop model of the plant under control to derive the set of fuzzy rules for the fuzzy controller. Of central interest are the stability, performance, and robustness of the resulting closed loop system. The major objective of model based fuzzy control is to use the full range of linear and nonlinear design and analysis methods to design such fuzzy controllers with better stability...

Native American History is a breakthrough reference guide, the first book of its kind to recognize and explore the rich, unfolding experiences of the indigenous American peoples as they evolved against a global backdrop.

Only one woman could win the...Heart of the Falcon.All her life, raven-haired Anqet had basked in the tranquility of Nefer...until the day her father died and her uncle descended upon the estate, hungry for her land, hungry for her. Desperate to escape his cruel obsession, she fled. But now, masquerading as a commoner in the magnificent city of Thebes, Anqet facesa new danger. Mysterious and seductive, Count Seth seems to be a soldier loyal to...