Computational determination of novel biomarkers of colon ...
Palaniappan, Ashok This work is a novel systems biology approach to decipher the identity of specific genes and gene products involved in the advancement of colon cancer from tumorigenesis through to metastasis. Stage-based meta-analysis of tumor genome-sequencing data in public domain was conducted and multiple approaches employed for mining novel genes driving the initiation, progression and metastasis of colon cancer. The consensus stage-specific driver genes...