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As the costs and resources of delivering health services have increased over the years, the importance of evaluating health services and interventions has become essential. An evaluation provides a systematic process of assessing the efficacy and efficiency of health services, including an assessment of their impact on beneficiaries, whether it be individuals or communities. Evaluation in the health sector includes the evaluation of burden dis...

With the rapid development of modern medical technology, endoscopic technology has also achieved unprecedented development. Its fields cover examination, treatment, surgery, and even molecular imaging diagnosis. Endoscopy technology brings a minimally invasive diagnosis and treatment experience to patients. Invasive treatment and examination of digestive surgery has changed from large incisions to several Trocar holes, from surgery to endoscop...

The process of drug discovery and development is a complex multistage logistics project spanned over 10-15 years with an average budget exceeding 1 billion USD. Starting with target identification and synthesizing anywhere between 10k to 15k synthetic compounds to potentially obtain the final drug that reaches the market involves a complicated maze with multiple inter- and intra-operative fields. Topics described in this book emphasize the pro...

The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital r...

The purpose of writing this book is to discuss the updated information on voice and swallowing disorders. The book has been written by international authors and experts in this field. You will find not only clinical aspects but also basic science aspects of voice and swallowing disorders. The chapters include the quantitative analysis of activity patterns of muscles of mastication and deglutition, and salivary secretion after facial massage an...

Alcohol fuels must remain as an essential component for the realization of a sustainable low-carbon society. Use of locally available, under-utilized feedstock becomes important for local energy security as well as an option for distributed energy infrastructure. Utilizing the available feedstock that has not been properly regarded as a legitimate resource due to economic and social reasons should be the focal point in the search for possible ...

This book has three sections on the role of technology in education. The first section covers the merits of online learning and environment. The second section of the book gives insight on new technologies in learning and teaching. The third section of the book underlines the importance of new tendencies for the technology in education. I have a firm belief that readers can find great insights on the role of technology in education from differ...

The subject of chaos has invaded practically every area of the natural sciences. Weather patterns are referred to as chaotic. There are chemical reactions and chaotic evolution of insect populations. Atomic and molecular physics have also seen the emergence of the study of chaos in these microscopic domains. This book examines the issue of chaos in nonlinear and dynamical systems, quantum mechanics, biology, and economics.

This book, Organic Polymers, covers aspects that are of immediate concern to a new entrant to the field of polymers. Taken as a whole, these eight chapters aim to help the readers easily assimilate other specialized and exhaustive treatises on the subject. Topics dealing with the chemistry and technology of polymers are presented in a careful and logical manner so as to provide an easy and enjoyable read. Several examples and analogies are inc...

Despite the significant burden of substance use disorders (SUD) across the world, SUD treatment systems face significant challenges to ensure immediate access to effective care. Prevention and treatment of SUDs is generally underfunded and its effectiveness to reduce substance use is frequently questioned. This book presents system level factors that may contribute to improving SUD prevention and treatment, particularly for underserved, and ra...

This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some...

Vascular malformations of the central nervous system are important pathologies that could present with abrupt onset hemorrhage resulting in devastating neurological deficits. Current knowledge of their biology and natural history is increasing. Diagnostic modalities help clinicians to better evaluate the individual cases, and to decide the best treatment options. Treatment alternatives are various and all treatment options should be evaluated ...

Recently, remarkable progress has been made in the area of preclinical xenotransplantation experiments. Surprisingly, a heterotopic heart from the gene-editing pig continued to beat for almost 2.5 years, when implanted in the monkey abdomen, and a pig life-supporting kidney could also function for over 1.3 years in monkeys. Concerning islets, islets from gene-editing pigs could work for more than one year in monkeys. It is noteworthy that one ...

Flavonoids with over 6000 natural colorful compounds are a unique class of phytonutrients found in almost all vegetables, fruits, and herbs. This book discusses the nature and role of these compounds by studying the molecular mechanism of flavonoids using spectroscopy and computational tools. The book also addresses the characteristics of natural vs. synthetic colors from both chemical and biological points of view. More importantly, a lengthy...

The book deliberately keeps background information to a minimum, instead it comprehensively covers adsorption of liquid solutions, the difference between equilibrium individual solute uptake and surface excess, a general discussion of adsorbate uptake mechanisms and uptake rate expression, uptake steps, performance models and their generalizations, application of performance models, and design methods based on the constant behavior assumption,...

The book, Nanorods and Nanocomposites aims to provide the reader with an overview of the recent advances made on the synthesis of nanorods and nanocomposites and their emerging applications for a better lifestyle. The nanorods are a surprising gift to materials science from the research field of nanoscale materials. Nanorods promise to serve as a building block of the next-generation electronic and optoelectronic devices. Nanocomposite materia...

This book is intended to attract the attention of practitioners and researchers in academia and industry interested in challenging paradigms of coding theory and computer vision. The chapters in this comprehensive reference explore the latest developments, methods, approaches, and applications of coding theory in a wide variety of fields and endeavours. This book is compiled with a view to provide researchers, academicians, and readers with an...

Lagoon Environments Around the World - A Scientific Perspective covers a wide range of topics. Typically bordering between land and sea, lagoons are among the most diversely utilized waterways on the planet. Lagoons are extremely important environments socio-economically, and their usage places ever increasing stress on these very sensitive aquatic regions. The effective management of shallow aquatic environments requires a detailed scientific...

The accurate prediction of multi-physical and multi-scale physical/chemical/mechanical processes in engineering remains a challenging problem despite considerable work in this area and the acceptance of finite element analysis and computational fluid dynamics as design tools. This book intends to provide the reader with an overview of the latest developments in computational techniques used in various engineering disciplines. The book includes...

Peter Wyngate's life is easy - viewed from the outside. Handsome, intelligent, athletic, musically talented, he can have any girl he wants. His father's a rich powerful man who can send his kid on European summer tours and bestow cool cars. He's got a great best friend and a fiercely loyal sister. In a matter of days at the end of the summer before heading to college, Peter learns that all the advantages of his life might actually be stumbling...