This report provides specific guidance for conducting accident analyses of nuclear power plants with modular high temperature gas cooled reactors (HTGRs). It contains details of initiating events and overviews of the safety aspects of events that could lead to fuel failure and potential activity release. Licensing type safety analyses, aimed at demonstration of sufficient safety margins, are also addressed, and suggestions for analysing various events related to the inherent safety features of HTGRs are given. The report is intended to supplement the IAEA Safety Standards Series publications.