Excerpt from Annual Report, Division of Intramural Research Programs, Vol. 2: October 1, 1987 September 30, 1988, Part II, Individual Project Reports

Although we have demonstrated the importance of cortical inputs to the limbic system in object recognition memory, we had not made as much progress in demonstrating the anatomical substrates responsible for the limbic feedback to the cortex that allows memories to be stored. A major hypothesis has been that the basal forebrain cholinergic system plays an important role in this process. But the relations of the basal forebrain to the medial temporal limbic areas and to the midline thalamus had not been completely described. Recent studies have addressed these issues.

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