Between the Lines of Men is a work of fiction following Don Freemont, a young psychologist in the 1950s who is obsessed with leaving behind an academic legacy. Don is one of the heads of a project sanctioned by the US government in which chemicals such as LSD are tested as weapons of war. When one of Don's subjects commits suicide, Don begins to feel guilty. With his future and legacy in mind, Don ends up becoming his own guinea pig which results in a hellish vision. His ego still clinging to life, Don sets out with intentions of forging a new legacy.