Since the first edition was published in 2006, this book has been acknowledged as the essential book on the practice. In this updated new edition, all chapters covering cancer sites have been significantly revised. Organized for specialists in several fields, it contains site-specific chapters that discuss how the evolving role of advanced image guidance has demonstrated greater efficacy and less toxicity. Clinical vignettes with images now accompany all site-specific chapters. The chapter on prostate brachytherapy has been expanded to include other indications in the genitourinary system, and there are two entirely new chapters—one chronicling the history of brachytherapy and the other detailing the emergence of skin brachytherapy.