Nacre, mother-of-pearl, is an exception from the rule that strength and toughness are generally mutually exclusive in materials. It possesses a unique set of mechanical properties which has been attributed to nacre's special brick-and-mortar-like microstructure. Consequently, mimicry of this microstructure for similar reinforcement in synthetic materials has been the goal of many researchers so far with excellent results in the area of thin films - but hardly any serviceable outcome in bulk dimensions.This thesis provides a way to fill this gap in processing of bulk-sized nacre-inspired composites. The approach is founded on sedimentation processes that can be rated as more facile, economically more efficient, and geometrically less limited than other methods. Eventually, it results in composites that mimic up to four structural design features of nacre, acting as examples for novel materials that could be applicable in fields ranging from ballistic protection to filtering technologies.