New edition of this classic text, updated to cover advances in psychiatry following publication of the DSM-5~Comprehensively covers basic science to clinical disorders to treatments~Provides in-depth descriptions of molecular, cellular, systems, and behavioral research~Includes detailed information on clinical research, spanning studies of epidemiology, nosology, disease etiology and pathophysiology, and treatment efficacy~Discusses state-of-the-art methodologies in the field, both basic and clinical