When a book is unearthed from an archeological site north of Lisbon, Portugal, a series of events are put in motion, resulting in the murders of the people trying to translate its cryptic writings. The Archon of Boston, a one thousand year-old vampire, sends her agent to retrieve the book when it arrives in Saint Albans, West Virginia. But he's not the only one searching for it. The body count rises as the search for the book goes on. Vampires and their ancient enemies clash with a few innocent humans caught in the middle.