Cytomegalovirus (CMV) Immunoglobulins, IgG and IgM were screened among HIV/AIDS clients to determine previous and recent infections respectively by ELISA technique. Immunological test (CD4 count) was used to ascertain the immune status of the clients studied. It is hoped that this research project would elucidate on the importance of screening CMV immunoglobulins during the management and care of AIDS by healthcare team especially when screening for AIDS related opportunistic infections.