Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma describes the intense research and clinical developments that required to optimize the available treatment options and the potential side effects to heal brain cancer. The success of this strategy includes the use of validated biomarkers, appropriate patient selection criteria, strategies to prevent adverse events, and the implementation of immunotherapy in multimodal treatment approach together with conventional therapies. In 18 chapters this title set forth the rationales for promising therapies like immunotherapy including immune checkpoint blockade, chimeric antigen receptor T (CAR T) cell therapy, oncolytic virotherapy, and vaccine therapy, in treating glioblastmoma, reviews the potential novel agents, the current status of preclinical and clinical trials, and discusses the challenges and future perspectives in glioblastoma immuno-oncology. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.