This study revealed that optimal family well-being was characterized by (a) mobilization of positive personal coping resources in dealing with stroke- related disability and daily care hassles, (b) realignment of personal competence in activities of daily living, (c) harmonization of intra-familial relationship, and (d) active and proactive management of care issues. Families who failed in part or in whole to maintain these four features were considered as having functional or dysfunctional well-being. The results are informative in enabling nurses to derive culturally- sensitive and community-based care strategies to help families living with stroke in Wuhan, China.