This specially curated collection features five reviews of current and key research on fruit losses and waste. The first chapter reviews the magnitude of losses and waste of fruit and vegetables as well as key issues in estimating losses. It provides a detailed assessment of the main causes of losses and waste together with strategies for their prevention. The second chapter assesses the adoption of new, non-destructive technologies as a way of measuring harvest maturity and improving sorting operations to minimise the risk of product loss and waste. The third chapter outlines the importance of harvest management of apples and considers the importance of various factors associated with fruit physiology, maturation and ripening to reduce losses. The fourth chapter reviews existing research in the preservation of fruit quality and reduction of post-harvest damage and loss by adopting suitable technologies and knowledge during post-harvest operation, storage management, transportation and marketing of mango fruit. The final chapter explores the advantages and disadvantages of cultivating ripening-impaired tomato mutants. It describes how controlling tomato diseases in both pre- and postharvest operations can help avoid fruit losses.