From individual tools to genome analysis, this book provides an overview of annotation strategies and toolkits currently in use. Presenting a combination of principles and practice, the authors elucidate database search engines and HTML-based annotation systems for specialists in computational biology and bioinformatics who use genome annotation in their work. They also introduce web service-based annotation pipelines. The text includes a CD-ROM with MAGPIE and Bluejay, genome annotation systems and viewers that are used in thousands of laboratories around the world.