When Josh Baker returns home unexpectedly from a secret mission with the Special Forces in Afghanistan, he finds his wife, Becky, with another man. The men struggle and Josh is knocked unconscious. The following day they are discovered, Josh, still unconscious, his wife dead. Now the prime suspect, Josh's defense is based on memory loss due to a concussion. Nevertheless, he is tried, found guilty and begins serving a life sentence at Butner Prison. There, attempts are made on his life. He begins having vivid nightmares. One night he awakens from a terrifying dream and realizes he has recognized the face of the killer. His memory is returning. He is determined to escape and try to prove his innocence. His cellmate and friend, Big Al, reminds him that no one has ever successfully fled from Butner. But Josh believes it's his only hope to save his life and shed the stigma of being Guilty until Proven Innocent.