Bovine mastitis, an inflammation of mammary glands, is the most important and costly disease in the dairy industry and affects the quality as well as quantity of milk. The control of bovine mastitis might be possible through improvement of husbandry and management practices such as herd size, type of farm, milk yield, ventilation status and cleanliness, etc in water buffaloes. The parity and age also effect on the incidence of mastitis.