This book constitutes the refereed proceedings of the 6th EAI International Conference on Industrial Networks and Intelligent Systems, INISCOM 2020, held in Hanoi, Vietnam, in August 2020. Due to COVID-19 pandemic the conference was held virtually. The 26 full papers were selected from 59 submissions and are organized thematically in tracks on telecommunications systems and networks, hardware, software and application designs, information processing and data analysis, industrial networks and intelligent systems, security and privacy.