This book constitutes the refereed proceedings of the International Conference on Intelligent Computing, ICIC 2006, held in Kunming, China, August 2006. The book collects 161 carefully chosen and revised full papers. Topical sections include neural networks, evolutionary computing and genetic algorithms, kernel methods, combinatorial and numerical optimization, multiobjective evolutionary algorithms, neural optimization and dynamic programming, as well as case-based reasoning and probabilistic reasoning.