86 short papers originating from the 13th International Symposium on Intracranial Pressure and Brain Monitoring held in July 2007 in San Francisco present experimental as well as clinical research data on invasive and non-invasive intracranial pressure and brain biochemistry monitoring. The papers have undergone a peer-reviewing and are organized in eight sections: brain injury: ICP management and cerebral physiology, hydrocephalus and cerebrospinal fluid dynamics, advanced neuromonitoring, biomedical informatics, imaging, ICP: brain compliance, biophysics, and biomechanics, stroke, subarachnoid hemorrhage, and intracerebral hematoma, and experimental studies and models. The papers address the increasing use of decompressive craniectomy for the treatment of brain edema as well after brain injury and the rapidly expanding field of advanced neuromonitoring and neuroimaging.