Excerpt from Journal of Cutaneous and Genito-Urinary Diseases, Vol. 20: September, 1902

Attention was directed to the matter in an accidental wav. It fre quently happened in the course of routine office work that suspicion of tuberculous disease was not raised until the bladder of the patient had been emptied in the making of the two-glasses test or for other rea son. It then becoming necessary to have some urine for bacteriologi cal examination. A clean.' sterilized catheter would be introduced for the purpose of obtaining it. This was often barelv more than would fill the catheter. And, on hypogastric pressure. Cause a few drops to fall into the test-tube. The soft catheter. Squeezed so as to hold its con tents safely. Would then be withdrawn. Its proximal end allowed to fall into the test-tube. And the urine to run out. It not infrequently hap pened that several drains of urine were obtained in this way. But that which filled the catheter was always added to the other. Dr. Johnson called mv attention to the fact that his examination of the speci mens thus obtained almost invariablv showed very large numbers of the bacilli. Often arranged in clumps and bundles. But also singly and scattered over the field. We were at first disposed to think the fault lav with the catheter. Or possibly that we were dealing with the smegma bacillus. Or even that the glycerine used to lubricate the catheter might have contained them. The first and last having been corrected and the whole technic of the procedure having been carefully guarded. The re sult remained the same. The bacilli were found thev appeared in exceptionallv large numbers.

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