This book provides the series of novel and significant compounds containing pyrazole substituted benzimidazoles which have been synthesized under environmental friendly microwave irradiation method. This book provides the simple, time saving and eco friendly method of synthesis of some novel benzimidazole derivatives which is an important pharmacophore for antimicrobial and anticancer drugs. The users of this book will be provided with novel synthetic routes for the synthesis of pyrazole bearing benzimidazoles and also the anti microbial, anticancer and anti tuberculosis activity screening has been carried out by simple methods.