The co-infection of onchocerciasis and malaria poses a threat to the overall health and well-being of persons in co-endemic areas and a challenge to relevant professionals and intervention agencies. In recent times, the complications arising from the use of conventional drugs for the treatment of these parasitic diseases have heightened, parasite drug resistance has escalated while anaphylactic shock and subsequent death have been reported in areas where Loa loa was co-endemic with onchocerciasis. Scholars burdened by these untoward effects have proposed the need for an effective and affordable drug regimen which will provide a simultaneous approach in the treatment of onchocerciasis and malaria. The book therefore provides a novel and effective drug regimen for the treatment of onchocerciasis, malaria and onchocerciasis-malaria co-infection. The clearance rates of the drug regimen on parasitemia among various age strata are succinctly highlighted while the onsets of action on single and mixed-infection are empirically presented. The contents are lucid, well-researched and will be useful to health-care and allied professionals as well as students of relevant disciplines.