This is an open access book.ICoBioSE stands for International Conference on Biology, Science and Education. ICoBioSE is the international conference held by the Biology Department and Master Program of Biology Education, Faculty of Mathematic and Sains, Universitas Negeri Padang. The aim of this international conference is to facilitate scientific publications of lecturers, biologists and biology education experts, diploma, master, and doctoral students and natural science experts. The scope of conference are botany, zoology, ecology, microbiology, genetics, molecular biology, bioinformatics, biochemistry, biophisic, environmental health, conservation and biology education.