This book constitutes the refereed proceedings of the 7th International Conference on Product-Focused Software Process Improvement, PROFES 2006, held in Amsterdam, June 2006. The volume presents 26 revised full papers and 12 revised short papers together with 6 reports on workshops and tutorials. The papers constitute a balanced mix of academic and industrial aspects, organized in topical sections on decision support, embedded software and system development, measurement, process improvement, and more.