This book provides a record of the family history of two particular branches of the Sailer and Strawbridge families in America. It concentrates on the ancestors of two individuals who lived in Philadelphia, Pennsylvania: Joseph Sailer, M.D. (1867-1928), and his wife, Mary Lowber Strawbridge (1875-1963). The book is divided into two main parts.Part A covers the history of several generations of Sailers, beginning with Wilhelm Sailer, who was born in New Jersey in 1758, and ending with the children of Joseph and Mary Sailer. Part B covers the Strawbridges, beginning with John Strawbridge, who was born in Ireland in the early 1700s and came to America around 1752.The book includes information about the births, deaths, and marriages of the individuals discussed, as well as some general information about their lives where available. It includes images of some family history documents such as letters, as well as some photographs of the persons discussed.The information in this book was compiled from family history documents and photographs accumulated over the years by the author, who is a descendant of the Sailer-Strawbridge family, and from research conducted by the author and others.